If youโre craving a Ultimate Beef and Cheddar Sandwich with Easy Cheese Sauce thatโs warm, savory, and incredibly satisfying, this homemade version delivers everything you loveโwithout a drive-thru. Tender roast beef, a rich homemade cheddar cheese sauce, and a soft onion roll come together in a comforting sandwich that feels nostalgic yet freshly made.
This recipe is simple enough for a weeknight dinner but indulgent enough to feel like a special treat. Best of all, you control the ingredients, the seasoning, and the meltiness of that irresistible cheese sauce.
Table of Contents
Why Youโll Love This Ultimate Beef and Cheddar Sandwich

There are plenty of reasons this sandwich earns a permanent spot in your recipe rotation.
First, the cheese sauce is homemade and incredibly easy. You only need a few pantry staples, and it comes together in minutes on the stovetop. No processed packets or complicated steps.
Second, the roast beef stays tender and juicy. By gently warming it instead of overcooking, you preserve its flavor and texture, which makes a huge difference.
Third, this sandwich is customizable. You can adjust the sharpness of the cheddar, add extra seasoning, or even swap the protein if needed.
Finally, itโs pure comfort food. Soft toasted rolls, savory beef, and silky cheese sauce create a combination thatโs filling, cozy, and deeply satisfying.
Ingredients for Ultimate Beef and Cheddar Sandwich
For the Sandwich
- Onion rolls or soft sandwich buns
- Thinly sliced deli roast beef
- Butter (for toasting the rolls)
For the Easy Cheese Sauce
- Butter
- All-purpose flour
- Milk
- Sharp cheddar cheese, freshly shredded
- Garlic powder
- Salt
- Black pepper
For the Savory Spread
- Mayonnaise
- Ketchup
- Worcestershire sauce
Ingredient Notes and Substitutions
Cheddar Cheese:
Sharp cheddar gives the sauce bold flavor, but mild or medium cheddar works if you prefer something gentler. For best melting, shred the cheese yourself rather than using pre-shredded.
Milk:
Whole milk makes the creamiest sauce, but 2% milk works well too. For a lighter option, use reduced-fat milk and slightly less cheese.
Roast Beef Substitutes:
If you donโt eat beef, thin-sliced roast turkey or chicken is a great alternative. For a vegetarian version, sautรฉed mushrooms or seasoned lentils provide a hearty swap.
Worcestershire Sauce:
If needed, you can replace it with a splash of soy sauce or a mix of soy sauce and a few drops of lemon juice.
Step-by-Step Instructions
Step 1: Toast the Rolls
Slice the onion rolls in half. Lightly butter the cut sides and toast them in a skillet or under a broiler until golden. Set aside while you prepare the filling.
Step 2: Make the Easy Cheese Sauce
In a medium saucepan over medium heat, melt the butter. Whisk in the flour and cook for about one minute until smooth and lightly bubbling.
Slowly pour in the milk, whisking constantly to prevent lumps. Continue cooking until the mixture thickens enough to coat the back of a spoon.
Reduce the heat to low and add the shredded cheddar cheese a handful at a time, stirring until fully melted. Season with garlic powder, salt, and black pepper. Keep warm on low heat.
Step 3: Warm the Roast Beef
Place the sliced roast beef in a skillet over low heat. Warm gently, turning occasionally, just until heated through. Avoid high heat so the beef stays tender.
Step 4: Mix the Savory Spread
In a small bowl, stir together mayonnaise, ketchup, and Worcestershire sauce until smooth. Taste and adjust if needed.
Step 5: Assemble the Sandwich
Spread a thin layer of the savory sauce on the bottom half of each toasted roll. Pile on warm roast beef, then generously spoon the melted cheese sauce over the top. Finish with the top bun and serve immediately.
Pro Tips for Success
- Shred your own cheese for the smoothest sauce.
- Keep the heat low once the cheese is added to avoid grainy texture.
- Warm the beef gentlyโnever boil or fry it hard.
- Toast the rolls lightly, so they stay soft but donโt get soggy.
- Serve right away for maximum melt and flavor.
Flavor Variations
Want to mix things up? Try one of these easy variations:
- Spicy Cheddar: Add a pinch of cayenne or a dash of hot sauce to the cheese sauce.
- Smoky Twist: Stir a little smoked paprika into the cheese sauce.
- Garlic Lovers: Add roasted garlic to the savory spread.
- Extra Cheesy: Use a blend of cheddar and mozzarella for extra stretch.
- Herb Boost: Sprinkle chopped parsley or chives over the beef before serving.
Serving Suggestions
This sandwich is hearty on its own, but it pairs beautifully with simple sides:
- Crispy oven fries or potato wedges
- Coleslaw or a light green salad
- Pickles or pickled onions for contrast
- Tomato soup for dipping
Itโs perfect for casual dinners, game-day spreads, or a fun weekend lunch.
Storage and Freezing Instructions
Refrigeration:
Store leftover roast beef and cheese sauce separately in airtight containers in the refrigerator for up to 3 days.
Reheating:
Warm the cheese sauce gently on the stovetop or microwave, stirring often. Heat the beef in a skillet over low heat.
Freezing:
The cheese sauce can be frozen for up to 2 months, though the texture may change slightly. Stir well while reheating to restore creaminess.

Ultimate Beef and Cheddar Sandwich with Easy Cheese Sauce
- Total Time: 25 minutes
- Yield: 4 sandwiches
Description
A warm, savory Ultimate Beef and Cheddar Sandwich made with tender roast beef, soft onion rolls, and an easy homemade cheddar cheese sauce for the ultimate comfort food experience.
Ingredients
- Onion rolls or soft sandwich buns
- Thinly sliced deli roast beef
- Butter for toasting the rolls
- Butter
- All-purpose flour
- Milk
- Sharp cheddar cheese, freshly shredded
- Garlic powder
- Salt
- Black pepper
- Mayonnaise
- Ketchup
- Worcestershire sauce
Instructions
- Slice the onion rolls in half, butter the cut sides, and toast until lightly golden.
- In a saucepan over medium heat, melt the butter and whisk in the flour until smooth.
- Slowly add the milk while whisking and cook until thickened.
- Reduce heat to low and stir in the shredded cheddar cheese until melted.
- Season the cheese sauce with garlic powder, salt, and black pepper and keep warm.
- Gently warm the sliced roast beef in a skillet over low heat.
- In a small bowl, mix mayonnaise, ketchup, and Worcestershire sauce until smooth.
- Spread the savory sauce on the bottom half of each roll.
- Layer warm roast beef over the sauce.
- Spoon generous amounts of cheese sauce over the beef.
- Top with the remaining roll half and serve immediately.
Notes
Keep the heat low when melting the cheese to maintain a smooth sauce and gently warm the beef to keep it tender and juicy.
- Prep Time: 10 minutes
- Cook Time: 15 minutes
- Category: Main Dish
- Method: Stovetop
- Cuisine: American
Nutrition Facts (Per Serving)
| Nutrient | Amount |
|---|---|
| Calories | ~520 |
| Protein | ~28g |
| Carbohydrates | ~34g |
| Fat | ~30g |
| Fiber | ~2g |
| Sodium | ~980mg |
Values are estimates and may vary based on ingredients used.
FAQ About Ultimate Beef and Cheddar Sandwich
Can I make the cheese sauce ahead of time?
Yes, you can prepare the cheese sauce up to two days in advance. Store it in the refrigerator and reheat gently, adding a splash of milk if needed to loosen it.
Whatโs the best roll for this sandwich?
Soft onion rolls work best because they complement the savory beef and cheese without overpowering them. Brioche buns are also a great option.
How do I keep the cheese sauce smooth?
Keep the heat low once the cheese is added and stir continuously. Avoid boiling, as high heat can cause the sauce to separate.
Can I use precooked beef?
Absolutely. Deli-sliced roast beef is ideal for this recipe because it heats quickly and stays tender.
Is this sandwich kid-friendly?
Yes, itโs mild, creamy, and very approachable. You can always reduce seasoning slightly for younger eaters.
Final Thoughts
This Ultimate Beef and Cheddar Sandwich with Easy Cheese Sauce proves that classic comfort food can be made better at home. With simple ingredients, quick steps, and bold, satisfying flavors, itโs a recipe youโll come back to again and again. Whether youโre feeding a family or treating yourself, this sandwich delivers warmth, nostalgia, and serious cheesy goodness in every bite.
